<International Circulation>: You have also done some work on heart rate recovery in exercise for patients with CRT.  Is this going to be a predictor for how patients react to CRT?

   《国际循环》：您也做过一些CRT患者心率复苏的工作。您认为，这能否用来预测患者对CRT疗法的反应？
 
    Prof. Thomas Dewland: That remains to be seen.  Our prior work was mainly done in athletes and in patients without cardiovascular disease.  We have not yet looked at heart rate recovery in patients with CRT.  There are important lessons to be learned as to which patients will truly benefit from ICDs.  We know that all patients with an ejection fraction (EF) of less that 35% are not all the same.  Trying to identify which patients are at a higher risk than others and may therefore benefit more from ICD therapy is important.  Heart rate variability， heart rate recovery， and other autonomic tone in general have all been postulated as mechanisms concerning this， but more research is definitely needed through future studies.

    Dewland教授：这还有待观察。我们之前的工作主要是针对运动员和没有心血管疾病的患者。我们还没有观察过采用CRT疗法的患者的心率复苏。了解究竟哪种患者能够真正从ICD的使用中获益是非常重要的一课。我们知道，射血分数（EF）小于35%的患者也是不尽相同的。识别出哪类患者风险更高，从而在ICD的治疗中获益更多是很重要的。心率具有变异性，心率复苏和其他一些自主神经张力通常被假定认为是其机制，但是在将来肯定还需要试验来对其进行进一步研究。